| 2021-05-30 17:00:4530 mayo 2021 | MÉRIDA A.D. (F)  | 17:00:4517:00 |  Sevilla FC SAD «B» |
| 2021-05-16 17:00:3316 mayo 2021 | UD Almería SAD  | 17:00:3317:00 | MÉRIDA A.D. (F) |
| 2021-05-09 17:00:109 mayo 2021 | MÉRIDA A.D. (F) | 17:00:1017:00 |  CD Hispalis |
| 2021-04-25 17:00:1925 abril 2021 | Málaga CF SAD «B»  | 17:00:1917:00 | MÉRIDA A.D. (F) |
| 2021-04-18 17:00:5518 abril 2021 | MÉRIDA A.D. (F) | 17:00:5517:00 |  CF Femenino Cáceres Atlético |
| 2021-04-11 17:00:2711 abril 2021 | CD Castuera Subastacar  | 17:00:2717:00 | MÉRIDA A.D. (F) |
| 2021-03-28 17:00:5128 marzo 2021 | MÉRIDA A.D. (F) | 17:00:5117:00 |  CD Santa Teresa «B» |
| 2021-03-21 17:00:2421 marzo 2021 | CD Badajoz Femenino  | 17:00:2417:00 | MÉRIDA A.D. (F) |
| 2021-03-14 17:00:2214 marzo 2021 | MÉRIDA A.D. (F) | 17:00:2217:00 |  Real Betis Balompié SAD «B» |
| 2021-02-28 17:00:1028 febrero 2021 | ADFB La Rambla  | 17:00:1017:00 | MÉRIDA A.D. (F) |
| 2021-02-21 17:00:2021 febrero 2021 | MÉRIDA A.D. (F) | 17:00:2017:00 |  Sporting de Huelva «B» |
| 2021-02-14 17:00:4214 febrero 2021 | CP San Miguel  | 17:00:4217:00 | MÉRIDA A.D. (F) |
| 2021-02-07 17:00:117 febrero 2021 | MÉRIDA A.D. (F) | 17:00:1117:00 |  Cádiz CF SAD |
| 2021-01-24 17:00:5724 enero 2021 | MÉRIDA A.D. (F) | 17:00:5717:00 | UD Almería SAD |
| 2021-01-21 10:49:4521 enero 2021 | Sevilla FC SAD «B» | 10:49:4510:49 | MÉRIDA A.D. (F) |
| 2021-01-17 17:00:3117 enero 2021 | CD Hispalis | 17:00:3117:00 | MÉRIDA A.D. (F) |
| 2021-01-10 17:00:5510 enero 2021 | MÉRIDA A.D. (F) | 17:00:5517:00 | Málaga CF SAD «B» |
| 2020-12-20 17:00:4920 diciembre 2020 | CF Femenino Cáceres Atlético | 17:00:4917:00 | MÉRIDA A.D. (F) |
| 2020-12-13 17:00:1113 diciembre 2020 | MÉRIDA A.D. (F) | 17:00:1117:00 | CD Castuera Subastacar |
| 2020-11-29 17:00:0029 noviembre 2020 | CD Santa Teresa «B» | 17:00:0017:00 | MÉRIDA A.D. (F) |
| 2020-11-22 17:00:1822 noviembre 2020 | MÉRIDA A.D. (F) | 1 - 2 | CD Badajoz Femenino |
| 2020-11-15 17:00:2015 noviembre 2020 | Real Betis Balompié SAD «B» | 17:00:2017:00 | MÉRIDA A.D. (F) |
| 2020-11-08 17:00:278 noviembre 2020 | MÉRIDA A.D. (F) | 2 - 3 | ADFB La Rambla |
| 2020-11-01 17:00:401 noviembre 2020 | Sporting de Huelva «B» | 0 - 0 | MÉRIDA A.D. (F) |
| 2020-10-25 17:00:4225 octubre 2020 | MÉRIDA A.D. (F) | 0 | CP San Miguel |
| 2020-10-11 12:00:4411 octubre 2020 | MÉRIDA A.D. (F) | 0 - 6 | CD Santa Teresa «B» |
| 2020-10-10 19:00:1710 octubre 2020 | MÉRIDA A.D. (F) | 0 - 2 |  CADIZ |
| 2020-10-04 12:00:524 octubre 2020 | MÉRIDA A.D. (F) | 1 - 1 | CP San Miguel |
| 2020-09-27 20:00:4527 septiembre 2020 | CP San Miguel | 1 - 0 | MÉRIDA A.D. (F) |
